Tolterodine Tartrate Information
Pronunciation
tole TER oh deen
What is this drug used for?
• It is used to treat an overactive bladder.
Frequently reported side effects of this drug
• Dizziness
• Fatigue
• Headache
• Abdominal pain
• Constipation
• Dry mouth
• Dry eyes
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
• Unable to pass urine
• Vision changes
• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Sound-alike/look-alike issues:
Tolterodine may be confused with fesoterodine, tolcapone
Detrol may be confused with Ditropan
Geriatric Patients: High-Risk Medication:
Beers Criteria: Tolterodine is identified in the Beers Criteria as a potentially inappropriate medication in patients 65 years and older due to its strong anticholinergic properties (Beers Criteria [AGS 2019]).
Storage and Stability
Store at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light.
Adverse Reactions
As reported with immediate release tablet, unless otherwise specified.
Cardiovascular: Chest pain
Central nervous system: Anxiety (extended release capsules), dizziness (immediate and extended release), drowsiness (immediate and extended release), fatigue (immediate and extended release), headache (immediate and extended release)
Dermatologic: Xeroderma
Endocrine & metabolic: Weight gain
Gastrointestinal: Abdominal pain (immediate and extended release), constipation (immediate and extended release), diarrhea, dyspepsia (immediate and extended release), xerostomia (more common with immediate release tablets)
Genitourinary: Dysuria (immediate and extended release)
Infection: Infection
Neuromuscular & skeletal: Arthralgia
Ophthalmic: Xerophthalmia (immediate and extended release), visual disturbance (immediate and extended release)
Respiratory: Bronchitis, flu-like symptoms, sinusitis (extended release)
Rare but important or life-threatening: Anaphylaxis, angioedema, confusion, dementia (aggravated), disorientation, hallucination, memory impairment, palpitations, peripheral edema, prolonged Q-T interval on ECG, tachycardia
