Ciprofloxacin Information
Pronunciation
sip roe FLOKS a sin
What is this drug used for?
• It is used to treat or prevent bacterial infections.
Frequently reported side effects of this drug
• Diarrhea
• Vomiting
• Nausea
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
• Tendon inflammation or rupture like pain, bruising, or swelling in the back of the ankle, shoulder, hand, or other joints
• Depression like thoughts of suicide, anxiety, emotional instability, agitation, irritability, panic attacks, mood changes, behavioral changes, or confusion
• Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin.
• Kidney problems like unable to pass urine, blood in the urine, change in amount of urine passed, or weight gain
• Nerve problems like sensitivity to heat or cold; decreased sense of touch; burning, numbness, or tingling; pain, or weakness in the arms, hands, legs, or feet
• Low blood sugar like dizziness, headache, fatigue, feeling weak, shaking, fast heartbeat, confusion, increased hunger, or sweating
• High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit
• Fast heartbeat
• Abnormal heartbeat
• Passing out
• Chest pain
• Thrush
• Severe loss of strength and energy
• Vision changes
• Sensing things that seem real but are not
• Seizures
• Severe headache
• Trouble sleeping
• Nightmares
• Dizziness
• Restlessness
• Shortness of breath
• Bruising
• Bleeding
• Tremors
• Abnormal gait
• Sunburn
• Chills
• Sore throat
• Vaginal pain, itching, and discharge
• Muscle pain
• Muscle weakness
• Difficulty focusing
• Trouble with memory
• Injection site irritation
• Severe or persistent pain in abdomen
• Severe or persistent chest pain
• Severe or persistent back pain
• Clostridioides (formerly Clostridium) difficile-associated diarrhea like abdominal pain or cramps, severe diarrhea or watery stools, or bloody stools
• Stevens-Johnson syndrome/toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes
• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Sound-alike/look-alike issues:
Ciprofloxacin may be confused with cephalexin
Cipro may be confused with Ceftin
Storage and Stability
Injection:
Premixed infusion: Store between 5°C to 25°C (41°F to 77°F); avoid freezing. Protect from light.
Vial: Store between 5°C to 30°C (41°F to 86°F); avoid freezing. Protect from light. Diluted solutions of 0.5 to 2 mg/mL in D51/4NS, D51/2NS, D5W, D10W, LR, NS are stable for up to 14 days refrigerated or at room temperature.
Microcapsules for oral suspension: Prior to reconstitution, store below 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from freezing. Following reconstitution, store at 25°C (77°F) for 14 days; excursions permitted to 15°C to 30°C (59°F to 86°F) for up to 14 days. Protect from freezing.
Tablet:
Immediate release: Store between 20°C to 25°C (68°F to 77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F).
Extended release: Store at 25°C (77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F).
Adverse Reactions
- Dermatologic: Skin rash
- Gastrointestinal: Abdominal pain (more common in children), diarrhea, dyspepsia, nausea, vomiting
- Genitourinary: Vulvovaginal candidiasis
- Hepatic: Abnormal hepatic function tests, increased serum alanine aminotransferase, increased serum aspartate aminotransferase
- Local: Injection site reactions (IV)
- Nervous system: Dizziness, headache, insomnia, nervousness, neurological signs and symptoms (IV: children), restlessness, somnolence
- Neuromuscular & skeletal: Musculoskeletal signs and symptoms (children)
- Respiratory: Asthma (children)
- Miscellaneous: Fever
