Aprecap (Emend / Aprepitant) 125/80 Kit – 3 caps


Each Aprecap comes with 3 casules and contain Aprepitant used to prevent nausea and vomiting induced by cancer chemotherapy.

Active Ingrediant: Aprepitant
Generic Name: Aprecap
Manufacturer: Glenmark
Strength: 125/80 Kit
Dosage Type: Capsule
Packaging Type: Foil in Box
Contains: 3 Caps

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Aprepitant Information


ap RE pi tant

What is this drug used for?

• It is used to prevent upset stomach and throwing up.

Frequently reported side effects of this drug

• Loss of strength and energy
• Diarrhea
• Lack of appetite
• Abdominal pain
• Hiccups
• Constipation
• Headache
• Heartburn

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Infection
• Severe dizziness
• Passing out
• Dry mouth
• Dry eyes
• Increased thirst
• Stevens-Johnson syndrome/toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes.
• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Medication Safety Issues

Sound-alike/look-alike issues:

Aprepitant may be confused with fosaprepitant, fosnetupitant, netupitant, rolapitant
Aprepitant IV (Cinvanti) may be confused with fosaprepitant IV (Emend for injection)
Emend (aprepitant) oral capsule/suspension formulations may be confused with Emend for injection (fosaprepitant)

Storage and Stability

Injection: Store intact vials at 2°C to 8°C (36°F to 46°F) or at room temperature for up to 60 days; do not freeze. When stored at ambient room temperature, solutions diluted for infusion in NS are stable for 6 hours and solutions diluted for infusion in D5W are stable for 12 hours. When refrigerated, solutions diluted for infusion in NS or D5W are stable for 72 hours.

Capsules: Store at room temperature of 20°C to 25°C (68°F to 77°F).

Oral suspension: Store unopened pouch at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F). Store in the original container. Do not open pouch until ready to use. Once prepared, if suspension is not used immediately, store refrigerated (between [2°C to 8°C/36°F to 46°F]) for up to 72 hours. When ready to use, the mixture may be kept at room temperature (between [20°C to 25°C/68°F to 77°F]) for up to 3 hours.

Adverse Reactions

Adverse reactions may be reported in combination with other antiemetic agents. As reported for highly emetogenic cancer chemotherapy or moderately emetogenic cancer chemotherapy, unless otherwise noted as reported for postoperative nausea and vomiting (PONV).

Cardiovascular: Bradycardia (PONV), flushing, hypotension (PONV), palpitations, peripheral edema, syncope (PONV)

Central nervous system: Abnormal behavior (children & adolescents), agitation (children & adolescents), anxiety, dizziness, fatigue (more common in adults), headache (children & adolescents), hypoesthesia (PONV), hypothermia (PONV), malaise, peripheral neuropathy

Dermatologic: Alopecia, hyperhidrosis, pruritus, skin rash, urticaria

Endocrine & metabolic: Decreased serum albumin (PONV), decreased serum potassium (PONV), decreased serum sodium, dehydration, hot flash, hypokalemia, hypovolemia (PONV), increased serum glucose (PONV), weight loss

Gastrointestinal: Abdominal pain, constipation (PONV), decreased appetite, diarrhea, dyspepsia, dysgeusia, eructation, flatulence, gastritis, gastroesophageal reflux disease, hiccups, nausea, vomiting, xerostomia

Genitourinary: Proteinuria

Hematologic & oncologic: Anemia, decreased hemoglobin (children & adolescents), decreased white blood cell count, febrile neutropenia, hematoma (PONV), neutropenia (more common in children & adolescents), thrombocytopenia

Hepatic: Increased serum alanine aminotransferase, increased serum alkaline phosphatase, increased serum aspartate aminotransferase, increased serum bilirubin (PONV)
Infection: Candidiasis, postoperative infection (PONV)
Local: Induration at injection site, inflammation at injection site, infusion site reaction
Neuromuscular & skeletal: Asthenia, musculoskeletal pain
Renal: Increased blood urea nitrogen
Respiratory: Cough, dyspnea, hypoxia (PONV), oropharyngeal pain, pharyngitis, respiratory depression (PONV)
Miscellaneous: Wound dehiscence (PONV)